Shuttle mutagenesis of Legionella pneumophila: identification of a gene associated with host cell cytopathicity.

We performed shuttle mutagenesis of Legionella pneumophila. Mutants were screened for reduced cellular infectivity. Approximately 10% of the mutants had decreased cytopathicity. The DNA sequence of one locus was determined; the inferred amino acid sequence revealed homology with transport proteins i...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Arroyo, J, Hurley, M C, Wolf, M, McClain, M S, Eisenstein, B I, Engleberg, N C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303072/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8063428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.9.4075-4080.1994
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