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Shuttle mutagenesis of Legionella pneumophila: identification of a gene associated with host cell cytopathicity.

We performed shuttle mutagenesis of Legionella pneumophila. Mutants were screened for reduced cellular infectivity. Approximately 10% of the mutants had decreased cytopathicity. The DNA sequence of one locus was determined; the inferred amino acid sequence revealed homology with transport proteins i...

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Autors principals: Arroyo, J, Hurley, M C, Wolf, M, McClain, M S, Eisenstein, B I, Engleberg, N C
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC303072/
https://ncbi.nlm.nih.gov/pubmed/8063428
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