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Tolerance to the rate-increasing and not rate-decreasing effects of pregnanolone in rats
Chronic treatment with benzodiazepines, which positively modulate GABA(A) receptors, can lead to the development of tolerance. Similar effects might also occur during chronic treatment with positive modulators acting at other sites on GABA(A) receptors (e.g., neuroactive steroids). In the current st...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3030679/ https://ncbi.nlm.nih.gov/pubmed/20859199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e32833fa79d |
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