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Effect of photobleaching on calibration model development in biological Raman spectroscopy

A major challenge in performing quantitative biological studies using Raman spectroscopy lies in overcoming the influence of the dominant sample fluorescence background. Moreover, the prediction accuracy of a calibration model can be severely compromised by the quenching of the endogenous fluorophor...

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Detalhes bibliográficos
Main Authors: Barman, Ishan, Kong, Chae-Ryon, Singh, Gajendra P., Dasari, Ramachandra R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Photo-Optical Instrumentation Engineers (SPIE) 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030610/
https://ncbi.nlm.nih.gov/pubmed/21280891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3520131
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