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An anti-idiotype antibody which mimics the inner-core region of lipopolysaccharide protects mice against a lethal challenge with endotoxin.

Recently, we described the generation and characterization of an Armenian hamster Ab2 beta anti-idiotype monoclonal antibody (MAb4G2) specific for the binding site of a mouse monoclonal antibody, MAbY1-4A6, directed against the conserved 2-keto-3-deoxyoctulosonate (Kdo)-containing inner-core region...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Field, S K, Morrison, D C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303058/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8063418/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.9.3994-3999.1994
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