Sildenafil Reduces Insulin-Resistance in Human Endothelial Cells

BACKGROUND: The efficacy of Phosphodiesterase 5 (PDE5) inhibitors to re-establish endothelial function is reduced in diabetic patients. Recent evidences suggest that therapy with PDE5 inhibitors, i.e. sildenafil, may increase the expression of nitric oxide synthase (NOS) proteins in the heart and ca...

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Bibliografiske detaljer
Main Authors: Mammi, Caterina, Pastore, Donatella, Lombardo, Marco F., Ferrelli, Francesca, Caprio, Massimiliano, Consoli, Claudia, Tesauro, Manfredi, Gatta, Lucia, Fini, Massimo, Federici, Massimo, Sbraccia, Paolo, Donadel, Giulia, Bellia, Alfonso, Rosano, Giuseppe M., Fabbri, Andrea, Lauro, Davide
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030559/
https://ncbi.nlm.nih.gov/pubmed/21297971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014542
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