Variable region sequences of a protective human monoclonal antibody specific for the Haemophilus influenzae type b capsular polysaccharide.

A hybridoma secreting a human immunoglobulin G2 kappa monoclonal antibody (MAb) specific for the capsular polysaccharide of Haemophilus influenzae type b (Hib) was isolated. This MAb, designated CA4, was bactericidal to Hib in vitro and protected infant rats from Hib bacteremia. Nucleotide sequence...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Lucas, A H, Larrick, J W, Reason, D C
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1994
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8063404/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.9.3873-3880.1994
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