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Kinetic Studies of the Arf Activator Arno on Model Membranes in the Presence of Arf Effectors Suggest Control by a Positive Feedback Loop

Proteins of the cytohesin/Arno/Grp1 family of Arf activators are positive regulators of the insulin-signaling pathway and control various remodeling events at the plasma membrane. Arno has a catalytic Sec7 domain, which promotes GDP to GTP exchange on Arf, followed by a pleckstrin homology (PH) doma...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stalder, Danièle, Barelli, Hélène, Gautier, Romain, Macia, Eric, Jackson, Catherine L., Antonny, Bruno
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030388/
https://ncbi.nlm.nih.gov/pubmed/21118813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.145532
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