Transactivation of the Epidermal Growth Factor Receptor by Heat Shock Protein 90 via Toll-like Receptor 4 Contributes to the Migration of Glioblastoma Cells

Extracellular heat shock protein HSP90α was reported to participate in tumor cell growth, invasion, and metastasis formation through poorly understood signaling pathways. Herein, we show that extracellular HSP90α favors cell migration of glioblastoma U87 cells. More specifically, externally applied...

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Main Authors: Thuringer, Dominique, Hammann, Arlette, Benikhlef, Naïma, Fourmaux, Eric, Bouchot, André, Wettstein, Guillaume, Solary, Eric, Garrido, Carmen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030348/
https://ncbi.nlm.nih.gov/pubmed/21127066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.154823
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