The NPC Motif of Aquaporin-11, Unlike the NPA Motif of Known Aquaporins, Is Essential for Full Expression of Molecular Function

The recently identified molecule aquaporin-11 (AQP11) has a unique amino acid sequence pattern that includes an Asn-Pro-Cys (NPC) motif, corresponding to the N-terminal Asn-Pro-Ala (NPA) signature motif of conventional AQPs. In this study, we examined the effect of the mutation of the NPC motif on t...

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Detalhes bibliográficos
Main Authors: Ikeda, Masahiro, Andoo, Ayaka, Shimono, Mariko, Takamatsu, Natsuko, Taki, Asaka, Muta, Kanako, Matsushita, Wataru, Uechi, Tamayo, Matsuzaki, Toshiyuki, Kenmochi, Naoya, Takata, Kuniaki, Sasaki, Sei, Ito, Katsuaki, Ishibashi, Kenichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030340/
https://ncbi.nlm.nih.gov/pubmed/21118806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.180968
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