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Purification and partial biochemical characterization of a Mycoplasma fermentans-derived substance that activates macrophages to release nitric oxide, tumor necrosis factor, and interleukin-6.

Mycoplasmal products may exert a number of diverse in vitro effects on cells of the immune system. A macrophage-activating substance from Mycoplasma fermentans was described in this laboratory and named mycoplasma-derived high-molecular-weight material (MDHM). Using synthesis of nitric oxide by peri...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Mühlradt, P F, Frisch, M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303034/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8063396/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.9.3801-3807.1994
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