LIMP-2 Links Late Phagosomal Trafficking with the Onset of the Innate Immune Response to Listeria monocytogenes: A ROLE IN MACROPHAGE ACTIVATION

The innate immune response to Listeria monocytogenes depends on phagosomal bacterial degradation by macrophages. Here, we describe the role of LIMP-2, a lysosomal type III transmembrane glycoprotein and scavenger-like protein, in Listeria phagocytosis. LIMP-2-deficient mice display a macrophage-rela...

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Detalhes bibliográficos
Main Authors: Carrasco-Marín, Eugenio, Fernández-Prieto, Lorena, Rodriguez-Del Rio, Estela, Madrazo-Toca, Fidel, Reinheckel, Thomas, Saftig, Paul, Alvarez-Dominguez, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030339/
https://ncbi.nlm.nih.gov/pubmed/21123180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.146761
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