Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence.

Previous studies have shown that the immune-regulated cytokine gamma interferon (IFN-gamma) activates host cells to restrict intracellular growth of the bacterial pathogen Chlamydia trachomatis by induction of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO). Recently, subinhibit...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Beatty, W L, Belanger, T A, Desai, A A, Morrison, R P, Byrne, G I
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8063385/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.9.3705-3711.1994
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