Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence.
Previous studies have shown that the immune-regulated cytokine gamma interferon (IFN-gamma) activates host cells to restrict intracellular growth of the bacterial pathogen Chlamydia trachomatis by induction of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO). Recently, subinhibit...
Guardat en:
| Publicat a: | Infect Immun |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1994
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8063385/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.62.9.3705-3711.1994 |
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