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Parvovirus B19 Nonstructural Protein-Induced Damage of Cellular DNA and Resultant Apoptosis

Parvovirus B19 is a widespread virus with diverse clinical presentations. The viral nonstructural protein, NS1, binds to and cleaves the viral genome, and induces apoptosis when transfected into nonpermissive cells, such as hepatocytes. We hypothesized that the cytotoxicity of NS1 in such cells resu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Poole, Brian D., Kivovich, Violetta, Gilbert, Leona, Naides, Stanley J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030141/
https://ncbi.nlm.nih.gov/pubmed/21278893
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