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Control of the specificity of T cell-mediated anti-idiotype immunity by natural regulatory T cells
The idiotypes of B cell lymphomas represent tumor-specific antigens. T cell responses induced by idiotype vaccination in vivo are directed predominantly against CDR peptides, whereas in vitro T cells also recognize framework-derived epitopes. To investigate the mechanisms regulating the specificity...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer-Verlag
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3029831/ https://ncbi.nlm.nih.gov/pubmed/20848095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0918-x |
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