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Symmetry, asymmetry, and kinetics of silencing establishment in Saccharomyces cerevisiae revealed by single-cell optical assays

In Saccharomyces cerevisiae, silent chromatin inhibits the expression of genes at the HML, HMR, and telomeric loci. When silent chromatin forms de novo, the rate of its establishment is influenced by different chromatin states. In particular, loss of the enzyme Dot1, an H3 K79 methyltransferase, lea...

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Bibliografiska uppgifter
Huvudupphovsmän: Osborne, Erin A., Hiraoka, Yasushi, Rine, Jasper
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029714/
https://ncbi.nlm.nih.gov/pubmed/21262833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018742108
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