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Symmetry, asymmetry, and kinetics of silencing establishment in Saccharomyces cerevisiae revealed by single-cell optical assays

In Saccharomyces cerevisiae, silent chromatin inhibits the expression of genes at the HML, HMR, and telomeric loci. When silent chromatin forms de novo, the rate of its establishment is influenced by different chromatin states. In particular, loss of the enzyme Dot1, an H3 K79 methyltransferase, lea...

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Detalles Bibliográficos
Autores principales: Osborne, Erin A., Hiraoka, Yasushi, Rine, Jasper
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029714/
https://ncbi.nlm.nih.gov/pubmed/21262833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018742108
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