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Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells

The 10S self-inhibited monomeric conformation of myosin II has been characterized extensively in vitro. Based upon its structural and functional characteristics, it has been proposed to be an assembly-competent myosin pool in equilibrium with filaments in cells. It is known that myosin filaments can...

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Autors principals: Milton, Deanna L., Schneck, Amy N., Ziech, Dominique A., Ba, Mariam, Facemyer, Kevin C., Halayko, Andrew J., Baker, Jonathan E., Gerthoffer, William T., Cremo, Christine R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029703/
https://ncbi.nlm.nih.gov/pubmed/21205888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011784108
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