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Antibody to Receptor Activator of NF-κB Ligand Ameliorates T Cell-Mediated Periodontal Bone Resorption

Activated T and B lymphocytes in periodontal disease lesions express receptor activator of NF-κB ligand (RANKL), which induces osteoclastic bone resorption. The objective of this study was to evaluate the effects of anti-RANKL antibody on periodontal bone resorption in vitro and in vivo. Aggregatiba...

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Autors principals: Lin, Xiaoping, Han, Xiaozhe, Kawai, Toshihisa, Taubman, Martin A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028846/
https://ncbi.nlm.nih.gov/pubmed/21078845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00944-10
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