Use of RmInt1, a Group IIB Intron Lacking the Intron-Encoded Protein Endonuclease Domain, in Gene Targeting

The group IIA intron Ll.LtrB from Lactococcus lactis and the group IIB intron EcI5 from Escherichia coli have intron-encoded proteins (IEP) with a DNA-binding domain (D) and an endonuclease domain (En). Both have been successfully retargeted to invade target DNAs other than their wild-type target si...

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Detalhes bibliográficos
Main Authors: García-Rodríguez, Fernando M., Barrientos-Durán, Antonio, Díaz-Prado, Vanessa, Fernández-López, Manuel, Toro, Nicolás
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028726/
https://ncbi.nlm.nih.gov/pubmed/21115708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02319-10
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