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A Transcriptional Regulator and ABC Transporters Link Stress Tolerance, (p)ppGpp, and Genetic Competence in Streptococcus mutans

Streptococcus mutans, a primary agent of dental caries, has three (p)ppGpp synthases: RelA, which is required for a mupirocin-induced stringent response; RelP, which produces (p)ppGpp during exponential growth and is regulated by the RelRS two-component system; and RelQ. Transcription of relPRS and...

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Detalles Bibliográficos
Main Authors: Seaton, Kinda, Ahn, Sang-Joon, Sagstetter, Ann M., Burne, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028664/
https://ncbi.nlm.nih.gov/pubmed/21148727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01257-10
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