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Protein Phosphatases Pph3, Ptc2, and Ptc3 Play Redundant Roles in DNA Double-Strand Break Repair by Homologous Recombination
In response to a DNA double-strand break (DSB), cells undergo a transient cell cycle arrest prior to mitosis until the break is repaired. In budding yeast (Saccharomyces cerevisiae), the DNA damage checkpoint is regulated by a signaling cascade of protein kinases, including Mec1 and Rad53. When DSB...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028631/ https://ncbi.nlm.nih.gov/pubmed/21135129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01168-10 |
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