Resequencing and Analysis of Variation in the TCF7L2 Gene in African Americans Suggests That SNP rs7903146 Is the Causal Diabetes Susceptibility Variant

OBJECTIVE: Variation in the transcription factor 7-like 2 (TCF7L2) locus is associated with type 2 diabetes across multiple ethnicities. The aim of this study was to elucidate which variant in TCF7L2 confers diabetes susceptibility in African Americans. RESEARCH DESIGN AND METHODS: Through the evalu...

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Autors principals: Palmer, Nicholette D., Hester, Jessica M., An, S. Sandy, Adeyemo, Adebowale, Rotimi, Charles, Langefeld, Carl D., Freedman, Barry I., Ng, Maggie C.Y., Bowden, Donald W.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2011
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028368/
https://ncbi.nlm.nih.gov/pubmed/20980453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0134
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