Airway Epithelial Indoleamine 2,3-Dioxygenase Inhibits CD4(+) T Cells during Aspergillus fumigatus Antigen Exposure

Indoleamine 2,3-dioxygenase (IDO) suppresses the functions of CD4(+) T cells through its ability to metabolize the essential amino acid tryptophan. Although the activity of IDO is required for the immunosuppression of allergic airway disease by the Toll-Like-Receptor 9 (TLR9) agonist, oligonucleotid...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Paveglio, Sara A., Allard, Jenna, Foster Hodgkins, Samantha R., Ather, Jennifer L., Bevelander, Mieke, Campbell, Jana Mayette, Whittaker LeClair, Laurie A., McCarthy, Sean M., van der Vliet, Albert, Suratt, Benjamin T., Boyson, Jonathan E., Uematsu, Satoshi, Akira, Shizuo, Poynter, Matthew E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2011
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028254/
https://ncbi.nlm.nih.gov/pubmed/20118221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0167OC
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