Suppression of lymphocyte and neutrophil functions by Pseudomonas aeruginosa mucoid exopolysaccharide (alginate): reversal by physicochemical, alginase, and specific monoclonal antibody treatments.

The mucoid exopolysaccharide (MEP or alginate) of Pseudomonas aeruginosa is thought to be a virulence factor for this organism by virtue of its ability to suppress local host defense mechanisms. We purified MEP from clinical isolates of mucoid P. aeruginosa, subjected it to degradation by ultrasonic...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Mai, G T, Seow, W K, Pier, G B, McCormack, J G, Thong, Y H
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302764/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8423085/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.2.559-564.1993
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