Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer

BACKGROUND: Vascular endothelial growth factor (VEGF) expression is up-regulated via a cyclooxygenase-2 (COX-2)-dependent mechanism in non-small cell lung cancer (NSCLC), but the specific signaling pathway involved is unclear. Our aim was to investigate the signaling pathway that links COX-2 with VE...

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Main Authors: Luo, Honghe, Chen, Zhenguang, Jin, Hui, Zhuang, Mei, Wang, Tao, Su, Chunhua, Lei, Yiyan, Zou, Jianyong, Zhong, Beilong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027119/
https://ncbi.nlm.nih.gov/pubmed/21219643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-6
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