Evaluation of the anti-angiogenic properties of the new selective α(V)β(3 )integrin antagonist RGDechiHCit

BACKGROUND: Integrins are heterodimeric receptors that play a critical role in cell-cell and cell-matrix adhesion processes. Among them, α(V)β(3 )integrin, that recognizes the aminoacidic RGD triad, is reported to be involved in angiogenesis, tissue repair and tumor growth. We have recently synthesi...

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Detalhes bibliográficos
Main Authors: Santulli, Gaetano, Basilicata, Maria Felicia, De Simone, Mariarosaria, Del Giudice, Carmine, Anastasio, Antonio, Sorriento, Daniela, Saviano, Michele, Del Gatto, Annarita, Trimarco, Bruno, Pedone, Carlo, Zaccaro, Laura, Iaccarino, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027097/
https://ncbi.nlm.nih.gov/pubmed/21232121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-7
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