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An in vitro model for Pelger-Huët anomaly: Stable knockdown of lamin B receptor in HL-60 cells

The principal human blood granulocyte (neutrophil) possesses a lobulated and deformable nucleus, important to facilitate rapid egress from blood vessels as these cells migrate to sites of bacterial or fungal infection. This unusual nuclear shape is a product of elevated levels of an integral membran...

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Détails bibliographiques
Auteurs principaux: Olins, Ada L, Ernst, Aurélie, Zwerger, Monika, Herrmann, Harald, Olins, Donald E
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027054/
https://ncbi.nlm.nih.gov/pubmed/21327094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.6.13271
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