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The mechanisms regulating the subcellular localization of AID

Activation induced deaminase (AID) is a unique enzyme that directly introduces mutations in the immunoglobulin genes to generate antibody diversity during the humoral immune response. Since this mutator enzyme poses a measurable risk of off-target mutation, which can be deleterious or transforming f...

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Bibliografski detalji
Glavni autori: Patenaude, Anne-Marie, Di Noia, Javier M
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027040/
https://ncbi.nlm.nih.gov/pubmed/21327080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.4.12107
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