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Meningococcal lipopolysaccharide (LPS)-derived oligosaccharide-protein conjugates evoke outer membrane protein- but not LPS-specific bactericidal antibodies in mice: influence of adjuvants.

Meningococcal lipopolysaccharide (LPS)-derived oligosaccharides (OS) were coupled to tetanus toxoid (TT) and purified P1.7,16 outer membrane proteins (OMP). The immunogenicities of the conjugates with and without the addition of the adjuvant Quil A or the nonionic block polymer L121 were studied in...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Verheul, A F, Van Gaans, J A, Wiertz, E J, Snippe, H, Verhoef, J, Poolman, J T
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302704/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8418041/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.1.187-196.1993
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