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Cystic fibrosis transmembrane regulator fragments with the Phe(508) deletion exert a dual allosteric control over the master kinase CK2
Cystic fibrosis mostly follows a single Phe(508) deletion in CFTR (cystic fibrosis transmembrane regulator) (CFTRΔF508), thereby causing premature fragmentation of the nascent protein with concomitant alterations of diverse cellular functions. We show that CK2, the most pleiotropic protein kinase, u...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3026963/ https://ncbi.nlm.nih.gov/pubmed/19925455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090813 |
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