Haplotype-Based Study of the Association of Alcohol Metabolizing Genes with Alcohol Dependence in Four Independent Populations

BACKGROUND: Ethanol is metabolized by two rate limiting reactions: alcohol dehydrogenases (ADH) convert ethanol to acetaldehyde, subsequently metabolized to acetate by aldehyde dehydrogenases (ALDH). Approximately 50% of East Asians have genetic variants that significantly impair this pathway and in...

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Main Authors: Liu, Jixia, Zhou, Zhifeng, Hodgkinson, Colin A., Yuan, Qiaoping, Shen, Pei-Hong, Mulligan, Connie J., Wang, Alex, Gray, Rebecca R., Roy, Alec, Virkkunen, Matti, Goldman, David, Enoch, Mary-Anne
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026908/
https://ncbi.nlm.nih.gov/pubmed/21083667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2010.01346.x
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