A Randomized Trial to Assess Anti-HIV Activity in Female Genital Tract Secretions and Soluble Mucosal Immunity Following Application of 1% Tenofovir Gel

BACKGROUND: Preclinical and early phase clinical microbicide studies have not consistently predicted the outcome of efficacy trials. To address this gap, candidate biomarkers of microbicide pharmacodynamics and safety were evaluated in a double-blind, placebo-controlled trial of tenofovir gel, the f...

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Main Authors: Keller, Marla J., Madan, Rebecca P., Torres, N. Merna, Fazzari, Melissa J., Cho, Sylvia, Kalyoussef, Sabah, Shust, Gail, Mesquita, Pedro M. M., Louissaint, Nicolette, Chen, Jianmeng, Cohen, Hillel W., Diament, Erin C., Lee, Anna C., Soto-Torres, Lydia, Hendrix, Craig W., Herold, Betsy C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026837/
https://ncbi.nlm.nih.gov/pubmed/21283552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016475
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