A Randomized Trial to Assess Anti-HIV Activity in Female Genital Tract Secretions and Soluble Mucosal Immunity Following Application of 1% Tenofovir Gel

BACKGROUND: Preclinical and early phase clinical microbicide studies have not consistently predicted the outcome of efficacy trials. To address this gap, candidate biomarkers of microbicide pharmacodynamics and safety were evaluated in a double-blind, placebo-controlled trial of tenofovir gel, the f...

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Bibliografische gegevens
Hoofdauteurs: Keller, Marla J., Madan, Rebecca P., Torres, N. Merna, Fazzari, Melissa J., Cho, Sylvia, Kalyoussef, Sabah, Shust, Gail, Mesquita, Pedro M. M., Louissaint, Nicolette, Chen, Jianmeng, Cohen, Hillel W., Diament, Erin C., Lee, Anna C., Soto-Torres, Lydia, Hendrix, Craig W., Herold, Betsy C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026837/
https://ncbi.nlm.nih.gov/pubmed/21283552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016475
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