A Randomized Trial to Assess Anti-HIV Activity in Female Genital Tract Secretions and Soluble Mucosal Immunity Following Application of 1% Tenofovir Gel

BACKGROUND: Preclinical and early phase clinical microbicide studies have not consistently predicted the outcome of efficacy trials. To address this gap, candidate biomarkers of microbicide pharmacodynamics and safety were evaluated in a double-blind, placebo-controlled trial of tenofovir gel, the f...

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Main Authors: Keller, Marla J., Madan, Rebecca P., Torres, N. Merna, Fazzari, Melissa J., Cho, Sylvia, Kalyoussef, Sabah, Shust, Gail, Mesquita, Pedro M. M., Louissaint, Nicolette, Chen, Jianmeng, Cohen, Hillel W., Diament, Erin C., Lee, Anna C., Soto-Torres, Lydia, Hendrix, Craig W., Herold, Betsy C.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2011
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026837/
https://ncbi.nlm.nih.gov/pubmed/21283552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016475
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