Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors

Tissue homeostasis and remodeling are processes that involve high turnover of biological macromolecules. Many of the waste molecules that are by-products or degradation intermediates of biological macromolecule turnover enter the circulation and are subsequently cleared by liver sinusoidal endotheli...

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Autores principales: Schledzewski, Kai, Géraud, Cyrill, Arnold, Bernd, Wang, Shijun, Gröne, Hermann-Josef, Kempf, Tibor, Wollert, Kai C., Straub, Beate K., Schirmacher, Peter, Demory, Alexandra, Schönhaber, Hiltrud, Gratchev, Alexei, Dietz, Lisa, Thierse, Hermann-Josef, Kzhyshkowska, Julia, Goerdt, Sergij
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026735/
https://ncbi.nlm.nih.gov/pubmed/21293057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44740
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