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GATA4 regulates Sertoli cell function and fertility in adult male mice

Transcription factor GATA4 is expressed in Sertoli and Leydig cells and is required for proper development of the murine fetal testis. The role of GATA4 in adult testicular function, however, has remained unclear due to prenatal lethality of mice harboring homozygous mutations in Gata4. To character...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kyrönlahti, Antti, Euler, Rosemarie, Bielinska, Malgorzata, Schoeller, Erica L., Moley, Kelle H., Toppari, Jorma, Heikinheimo, Markku, Wilson, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026658/
https://ncbi.nlm.nih.gov/pubmed/21172404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2010.12.019
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