Progressive but Previously Untreated CLL Patients with Greater Array CGH Complexity Exhibit a Less Durable Response to Chemoimmunotherapy

To better understand the implications of genomic instability and outcome in B-cell CLL, we sought to address genomic complexity as a predictor of chemosensitivity and ultimately clinical outcome in this disease. We employed array-based comparative genomic hybridization (aCGH), using a one-million pr...

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Detalhes bibliográficos
Main Authors: Kay, Neil E., Eckel-Passow, Jeanette E., Braggio, Esteban, VanWier, Scott, Shanafelt, Tait D., Van Dyke, Daniel L., Jelinek, Diane F., Tschumper, Renee C., Kipps, Thomas, Byrd, John C., Fonseca, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026606/
https://ncbi.nlm.nih.gov/pubmed/21156228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2010.09.003
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