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A place for everything: Chromosomal integration of large constructs

We have developed an easy, reliable two-step method for the insertion of large DNA fragments into any desired location in the E. coli chromosome. The method is based on the recombineering of a small (∼1.3 kbp) “Landing Pad” into the chromosome at the insertion site, to which the large construct is s...

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Détails bibliographiques
Auteurs principaux: Kuhlman, Thomas E, Cox, Edward C
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026472/
https://ncbi.nlm.nih.gov/pubmed/21327065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.4.12386
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