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The use of Listeria monocytogenes as a DNA delivery vector for cancer gene therapy

Listeria monocytogenes is an intracellular pathogen that lyses the phagosomal vacuole of infected cells, proliferates in the host cell cytoplasm and can actively enter adjacent cells. The pathogen is therefore well suited to exploitation as a vector for the delivery of DNA to target cells as the lif...

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Bibliographic Details
Main Authors: Tangney, Mark, van Pijkeren, Jan Peter, Gahan, Cormac GM
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026469/
https://ncbi.nlm.nih.gov/pubmed/21327062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.4.11725
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