Insulin/FOXO Signaling Regulates Ovarian Prostaglandins Critical for Reproduction

Abnormalities in insulin/IGF-1 signaling are associated with infertility, but the molecular mechanisms are not well understood. Here we use liquid chromatography with electrospray ionization tandem mass spectrometry to show that the C. elegans insulin/FOXO pathway regulates the metabolism of locally...

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Detalhes bibliográficos
Main Authors: Edmonds, Johnathan W., Prasain, Jeevan K., Dorand, Dixon, Yang, Youfeng, Hoang, Hieu D., Vibbert, Jack, Kubagawa, Homare M., Miller, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026445/
https://ncbi.nlm.nih.gov/pubmed/21145501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.11.005
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