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Homologous expression of aspartokinase (ask) gene in Streptomyces clavuligerus and its hom-deleted mutant: Effects on cephamycin C production

In this study, the effect of homologous multiple copies of the ask gene, which encodes aspartokinase catalyzing the first step of the aspartate pathway, on cephamycin C biosynthesis in S. clavuligerus NRRL 3585 and its hom mutant was investigated. The intracellular pool levels of aspartate pathway a...

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Auteurs principaux: Özcengiz, Gülay, Okay, Sezer, Ünsaldı, Eser, Taşkın, Bilgin, Liras, Paloma, Piret, Jacqueline
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026424/
https://ncbi.nlm.nih.gov/pubmed/21326925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.1.3.11244
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