Regional correlation of emphysematous changes in lung function and structure: a comparison between pulmonary function testing and hyperpolarized MRI metrics

Regional and global relationships of lung function and structure were studied using hyperpolarized (3)He MRI in a rat elastase-induced model of emphysema (n = 4) and healthy controls (n = 5). Fractional ventilation (r) and apparent diffusion coefficient (ADC) of (3)He were measured at a submillimete...

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Main Authors: Emami, Kiarash, Chia, Elaine, Kadlecek, Stephen, MacDuffie-Woodburn, John P., Zhu, Jianliang, Pickup, Stephen, Blum, Allison, Ishii, Masaru, Rizi, Rahim R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026352/
https://ncbi.nlm.nih.gov/pubmed/20884833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00269.2010
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