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Genome-Wide Analysis of PDZ Domain Binding Reveals Inherent Functional Overlap within the PDZ Interaction Network

Binding selectivity and cross-reactivity within one of the largest and most abundant interaction domain families, the PDZ family, has long been enigmatic. The complete human PDZ domain complement (the PDZome) consists of 267 domains and we applied here a Bayesian selectivity model to predict hundred...

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書誌詳細
主要な著者: te Velthuis, Aartjan J. W., Sakalis, Philippe A., Fowler, Donald A., Bagowski, Christoph P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026046/
https://ncbi.nlm.nih.gov/pubmed/21283644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016047
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