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Global analysis of estrogen receptor beta binding to breast cancer cell genome reveals an extensive interplay with estrogen receptor alpha for target gene regulation

BACKGROUND: Estrogen receptors alpha (ERα) and beta (ERβ) are transcription factors (TFs) that mediate estrogen signaling and define the hormone-responsive phenotype of breast cancer (BC). The two receptors can be found co-expressed and play specific, often opposite, roles, with ERβ being able to mo...

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Bibliografiske detaljer
Main Authors: Grober, Oli MV, Mutarelli, Margherita, Giurato, Giorgio, Ravo, Maria, Cicatiello, Luigi, De Filippo, Maria Rosaria, Ferraro, Lorenzo, Nassa, Giovanni, Papa, Maria Francesca, Paris, Ornella, Tarallo, Roberta, Luo, Shujun, Schroth, Gary P, Benes, Vladimir, Weisz, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025958/
https://ncbi.nlm.nih.gov/pubmed/21235772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-36
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