Testing the thrifty gene hypothesis: the Gly482Ser variant in PPARGC1A is associated with BMI in Tongans

BACKGROUND: The thrifty gene hypothesis posits that, in populations that experienced periods of feast and famine, natural selection favoured individuals carrying thrifty alleles that promote the storage of fat and energy. Polynesians likely experienced long periods of cold stress and starvation duri...

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Detalhes bibliográficos
Main Authors: Myles, Sean, Lea, Rod A, Ohashi, Jun, Chambers, Geoff K, Weiss, Joerg G, Hardouin, Emilie, Engelken, Johannes, Macartney-Coxson, Donia P, Eccles, David A, Naka, Izumi, Kimura, Ryosuke, Inaoka, Tsukasa, Matsumura, Yasuhiro, Stoneking, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025936/
https://ncbi.nlm.nih.gov/pubmed/21244673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-10
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