Single-Nucleotide Polymorphisms in LPA Explain Most of the Ancestry-Specific Variation in Lp(a) Levels in African Americans

Lipoprotein(a) (Lp(a)) is an important causal cardiovascular risk factor, with serum Lp(a) levels predicting atherosclerotic heart disease and genetic determinants of Lp(a) levels showing association with myocardial infarction. Lp(a) levels vary widely between populations, with African-derived popul...

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Autori principali: Deo, Rahul C., Wilson, James G., Xing, Chao, Lawson, Kim, Kao, W. H. Linda, Reich, David, Tandon, Arti, Akylbekova, Ermeg, Patterson, Nick, Mosley, Thomas H., Boerwinkle, Eric, Taylor, Herman A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025914/
https://ncbi.nlm.nih.gov/pubmed/21283670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014581
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