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Evidence for recycling of external guide sequences during cleavage of bipartite substrates in vitro by reconstituted archaeal RNase P
RNA-mediated RNA cleavage events are being increasingly exploited to disrupt RNA function, an important objective in post-genomic biology. RNase P, a ribonucleoprotein enzyme, which catalyzes the removal of 5′-leaders from precursor tRNAs (pre-tRNAs), has previously been utilized for targeted degrad...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025773/ https://ncbi.nlm.nih.gov/pubmed/21144851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.11.056 |
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