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PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation

The tumor suppressors phosphatase and tensin homologue deleted on chromosome ten (PTEN) and p53 are closely related to the pathogenesis of breast cancer, yet pathway-specific mechanisms underlying their participation in mediating the protective actions of dietary bioactive components on breast cance...

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Detalhes bibliográficos
Main Authors: Rahal, Omar M., Simmen, Rosalia C.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025717/
https://ncbi.nlm.nih.gov/pubmed/20554748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq123
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