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Novel free paclitaxel-loaded poly(L-γ-glutamylglutamine)–paclitaxel nanoparticles
The purpose of this study was to develop a novel formulation of paclitaxel (PTX) that would improve its therapeutic index. Here, we combined a concept of polymer–PTX drug conjugate with a concept of polymeric micelle drug delivery to form novel free PTX-loaded poly(L-γ-glutamylglutamine) (PGG)–PTX c...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Dove Medical Press
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025592/ https://ncbi.nlm.nih.gov/pubmed/21289985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S15839 |
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