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Prion amyloid structure explains templating: how proteins can be genes

The yeast and fungal prions determine heritable and infectious traits, and are thus genes composed of protein. Most prions are inactive forms of a normal protein as it forms a self-propagating filamentous β – sheet - rich polymer structure called amyloid. Remarkably, a single prion protein sequence...

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Détails bibliographiques
Auteurs principaux: Wickner, Reed B., Shewmaker, Frank, Edskes, Herman, Kryndushkin, Dmitry, Nemecek, Julie, McGlinchey, Ryan, Bateman, David, Winchester, Chia-Lin
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025496/
https://ncbi.nlm.nih.gov/pubmed/20726897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1567-1364.2010.00666.x
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