Multiple elements in the eIF4G1 N-terminus promote assembly of eIF4G1•PABP mRNPs in vivo

eIF4G is the scaffold subunit of the eIF4F complex, whose binding domains for eIF4E and poly(A)-binding protein (PABP) are thought to enhance formation of activated eIF4F•mRNA•PABP complexes competent to recruit 43S pre-initiation complexes. We found that the RNA-binding region (RNA1) in the N-termi...

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Detaylı Bibliyografya
Asıl Yazarlar: Park, Eun-Hee, Walker, Sarah E, Lee, Joseph M, Rothenburg, Stefan, Lorsch, Jon R, Hinnebusch, Alan G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025458/
https://ncbi.nlm.nih.gov/pubmed/21139564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.312
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