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Polyclonal Adaptive Regulatory CD4 Cells That Can Reverse Type I Diabetes Become Oligoclonal Long-Term Protective Memory Cells

Type 1 diabetes is a CD4 cell-dependent disease that results from destruction of insulin-producing β cells in pancreatic islets. An ideal therapy would reverse diabetes shortly after onset when islet function in not yet fully ablated, and also prevent re-emergence of disease through the generation o...

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Detalhes bibliográficos
Main Authors: Godebu, Elana, Summers-Torres, Daphne, Lin, Melissa M., Baaten, Bas J. G., Bradley, Linda M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025323/
https://ncbi.nlm.nih.gov/pubmed/18641317
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